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Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children

AIMS: Paracetamol has a central action for both antipyresis and analgesia. Maximum temperature decrease and peak analgesia are reported at 1–2 h after peak plasma paracetamol concentration. We wished to determine the relationship between plasma and cerebrospinal fluid (CSF) pharmacokinetics in child...

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Bibliografske podrobnosti
Main Authors: Anderson, B J, Holford, N H G, Woollard, G A, Chan, P L S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873683/
https://ncbi.nlm.nih.gov/pubmed/9764964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00780.x
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