Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children

AIMS: This study was designed to characterize paediatric pharmacokinetics and central nervous system exposure of flurbiprofen. METHODS: The pharmacokinetics of flurbiprofen were studied in 64 healthy children aged 3 months to 13 years, undergoing surgery with spinal anaesthesia. Children were admini...

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Bibliographic Details
Main Authors: Kumpulainen, Elina, Välitalo, Pyry, Kokki, Merja, Lehtonen, Marko, Hooker, Andrew, Ranta, Veli-Pekka, Kokki, Hannu
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
Subjects:
Paediatric Clinical Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950990/
https://ncbi.nlm.nih.gov/pubmed/20840447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03720.x
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