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Pharmacokinetics of tranexamic acid in neonates and infants undergoing cardiac surgery

AIM: Tranexamic acid (TXA) continues to be one of the antifibrinolytics of choice during paediatric cardiac surgery. However, in infants less than 1 year of age, the optimal dosing based on pharmacokinetic (PK) considerations is still under discussion. METHODS: Forty‐three children less than 1 year...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Gertler, Ralph, Gruber, Michael, Grassin‐Delyle, Stanislas, Urien, Saïk, Martin, Klaus, Tassani‐Prell, Peter, Braun, Siegmund, Burg, Simon, Wiesner, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510067/
https://ncbi.nlm.nih.gov/pubmed/28245519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13274
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