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Pharmacokinetics of cefuroxime in infants and neonates undergoing cardiac surgery

AIMS: Very little data exist regarding the effect of cardiopulmonary bypass (CPB) on cefuroxime (CXM) pharmacokinetics in children less than one year of age. METHODS: 50 mg kg(−1) CXM i.v. after induction were followed by 75 mg kg(−1) into the CPB circuit. In 42 patients undergoing cardiac surgery,...

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Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Gertler, Ralph, Gruber, Michael, Wiesner, Gunther, Grassin‐Delyle, Stanislas, Urien, Saïk, Tassani‐Prell, Peter, Martin, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089814/
https://ncbi.nlm.nih.gov/pubmed/29761538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13632
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