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Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

AIMS: The present study was conducted to evaluate metabolism of the enantiomers of verapamil and norverapamil using a broad range of cytochrome P450 isoforms and measure the kinetic parameters of these processes. METHODS: Cytochrome P450 cDNA-expressed cells and microsomes from a P450-expressed lymp...

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Autors principals: Tracy, Timothy S, Korzekwa, Kenneth R, Gonzalez, Frank J, Wainer, Irving W
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014179/
https://ncbi.nlm.nih.gov/pubmed/10336579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00923.x
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