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Enantiomers of Naringenin as Pleiotropic, Stereoselective Inhibitors of Cytochrome P450 Isoforms

Interactions between naringenin and the cytochrome P450 (CYP) system have been of interest since the first demonstration that grapefruit juice reduced CYP3A activity. The effects of naringenin on other CYP isoforms have been less investigated. In addition, it is well known that interactions with enz...

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Detalhes bibliográficos
Main Authors: Lu, Wenjie Jessie, Ferlito, Valentina, Xu, Cong, Flockhart, David A, Caccamese, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252466/
https://ncbi.nlm.nih.gov/pubmed/21953762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.21005
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