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Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

AIMS: To identify the human cytochrome P450 enzyme(s) involved in the in vitro metabolism of rosiglitazone, a potential oral antidiabetic agent for the treatment of type 2 diabetes-mellitus. METHOD: The specific P450 enzymes involved in the metabolism of rosiglitazone were determined by a combinatio...

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Detalhes bibliográficos
Main Authors: Baldwin, S J, Clarke, S E, Chenery, R J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014317/
https://ncbi.nlm.nih.gov/pubmed/10510156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00030.x
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