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Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone
AIMS: To identify the human cytochrome P450 enzyme(s) involved in the in vitro metabolism of rosiglitazone, a potential oral antidiabetic agent for the treatment of type 2 diabetes-mellitus. METHOD: The specific P450 enzymes involved in the metabolism of rosiglitazone were determined by a combinatio...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014317/ https://ncbi.nlm.nih.gov/pubmed/10510156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00030.x |
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