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Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions

1. Cisapride is a prokinetic drug that is widely used to facilitate gastrointestinal tract motility. 2. Structurally, cisapride is a substituted piperidinyl benzamide that interacts with 5-hydroxytryptamine-4 receptors and which is largely without central depressant or antidopaminergic side-effects....

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Bibliografiska uppgifter
Huvudupphovsmän: Bohets, H, Lavrijsen, K, Hendrickx, J, van Houdt, J, van Genechten, V, Verboven, P, Meuldermans, W, Heykants, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572003/
https://ncbi.nlm.nih.gov/pubmed/10780971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703246
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