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Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism

Cytochrome P450 (P450) protein-protein interactions have been shown to alter their catalytic activity. Furthermore, these interactions are isoform specific and can elicit activation, inhibition, or no effect on enzymatic activity. Studies show that these effects are also dependent on the protein par...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Bostick, Chris D., Hickey, Katherine M., Wollenberg, Lance A., Flora, Darcy R., Tracy, Timothy S., Gannett, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851305/
https://ncbi.nlm.nih.gov/pubmed/26961240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.067637
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