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The Use of Immobilized Cytochrome P4502C9 in PMMA-Based Plug-Flow Bioreactors for the Production of Drug Metabolites
Cytochrome P450 enzymes play a key role in the metabolism of pharmaceutical agents. To determine metabolite toxicity, it is necessary to obtain P450 metabolites from various pharmaceutical agents. Here, we describe a bioreactor that is made by immobilizing cytochrome P450 2C9 (CYP2C9) to a poly (met...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943684/ https://ncbi.nlm.nih.gov/pubmed/24166101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-013-0537-z |
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