Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

Mutations in mutS and mutL, which encode DNA mismatch repair (MMR) proteins, can confer hypermutator phenotypes and may facilitate the emergence of mutational antibiotic resistance in bacteria. Linezolid-resistant enterococci (LRE) rarely emerge during therapy and contain mutations in 23S rRNA genes...

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Detalhes bibliográficos
Main Authors: Willems, Rob J., Top, Janetta, Smith, Derek J., Roper, David I., North, Sarah E., Woodford, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201155/
https://ncbi.nlm.nih.gov/pubmed/14506009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3061-3066.2003
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