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Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

Mutations in mutS and mutL, which encode DNA mismatch repair (MMR) proteins, can confer hypermutator phenotypes and may facilitate the emergence of mutational antibiotic resistance in bacteria. Linezolid-resistant enterococci (LRE) rarely emerge during therapy and contain mutations in 23S rRNA genes...

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Main Authors: Willems, Rob J., Top, Janetta, Smith, Derek J., Roper, David I., North, Sarah E., Woodford, Neil
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC201155/
https://ncbi.nlm.nih.gov/pubmed/14506009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3061-3066.2003
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