Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

Mutations in mutS and mutL, which encode DNA mismatch repair (MMR) proteins, can confer hypermutator phenotypes and may facilitate the emergence of mutational antibiotic resistance in bacteria. Linezolid-resistant enterococci (LRE) rarely emerge during therapy and contain mutations in 23S rRNA genes...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Willems, Rob J., Top, Janetta, Smith, Derek J., Roper, David I., North, Sarah E., Woodford, Neil
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Mechanisms of Resistance
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3061-3066.2003
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