Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

Mutations in mutS and mutL, which encode DNA mismatch repair (MMR) proteins, can confer hypermutator phenotypes and may facilitate the emergence of mutational antibiotic resistance in bacteria. Linezolid-resistant enterococci (LRE) rarely emerge during therapy and contain mutations in 23S rRNA genes...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Willems, Rob J., Top, Janetta, Smith, Derek J., Roper, David I., North, Sarah E., Woodford, Neil
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2003
Aiheet:	Mechanisms of Resistance
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3061-3066.2003
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