Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

The inhibitor of apoptosis protein survivin has been implicated in both cell cycle control and apoptosis resistance. To discriminate between these different roles, we used transgenic expression of survivin in the skin as a model for cell proliferation, differentiation, and apoptosis. Transgenic mice...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Grossman, Douglas, Kim, Paul J., Blanc-Brude, Olivier P., Brash, Douglas E., Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13345
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