Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

The inhibitor of apoptosis protein survivin has been implicated in both cell cycle control and apoptosis resistance. To discriminate between these different roles, we used transgenic expression of survivin in the skin as a model for cell proliferation, differentiation, and apoptosis. Transgenic mice...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grossman, Douglas, Kim, Paul J., Blanc-Brude, Olivier P., Brash, Douglas E., Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2001
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC200956/
https://ncbi.nlm.nih.gov/pubmed/11581300
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