Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

The inhibitor of apoptosis protein survivin has been implicated in both cell cycle control and apoptosis resistance. To discriminate between these different roles, we used transgenic expression of survivin in the skin as a model for cell proliferation, differentiation, and apoptosis. Transgenic mice...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Grossman, Douglas, Kim, Paul J., Blanc-Brude, Olivier P., Brash, Douglas E., Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2001
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13345
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