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Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

The inhibitor of apoptosis protein survivin has been implicated in both cell cycle control and apoptosis resistance. To discriminate between these different roles, we used transgenic expression of survivin in the skin as a model for cell proliferation, differentiation, and apoptosis. Transgenic mice...

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書誌詳細
出版年:J Clin Invest
主要な著者: Grossman, Douglas, Kim, Paul J., Blanc-Brude, Olivier P., Brash, Douglas E., Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13345
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