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Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge

IL-17 has been implicated in a number of inflammatory diseases, but the conditions of antigen exposure that drive the generation of Th17 responses have not been well defined. Epicutaneous (EC) immunization of mice with ovalbumin (OVA), which causes allergic skin inflammation with many characteristic...

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Bibliographic Details
Main Authors: He, Rui, Oyoshi, Michiko K., Jin, Haoli, Geha, Raif S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000444/
https://ncbi.nlm.nih.gov/pubmed/17893340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706942104
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