Suppression of p53-dependent senescence by the JNK signal transduction pathway

The JNK signaling pathway is implicated in the regulation of the AP1 transcription factor and cell proliferation. Here, we examine the role of JNK by using conditional and chemical genetic alleles of the ubiquitously expressed murine genes that encode the isoforms JNK1 and JNK2. Our analysis demonst...

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Bibliographische Detailangaben
Hauptverfasser: Das, Madhumita, Jiang, Feng, Sluss, Hayla K., Zhang, Chao, Shokat, Kevan M., Flavell, Richard A., Davis, Roger J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000443/
https://ncbi.nlm.nih.gov/pubmed/17893331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707782104
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