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JNK regulates FoxO-dependent autophagy in neurons

The cJun N-terminal kinase (JNK) signal transduction pathway is implicated in the regulation of neuronal function. JNK is encoded by three genes that play partially redundant roles. Here we report the creation of mice with targeted ablation of all three Jnk genes in neurons. Compound JNK-deficient n...

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Detalhes bibliográficos
Main Authors: Xu, Ping, Das, Madhumita, Reilly, Judith, Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042155/
https://ncbi.nlm.nih.gov/pubmed/21325132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1984311
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