JNK regulates FoxO-dependent autophagy in neurons

The cJun N-terminal kinase (JNK) signal transduction pathway is implicated in the regulation of neuronal function. JNK is encoded by three genes that play partially redundant roles. Here we report the creation of mice with targeted ablation of all three Jnk genes in neurons. Compound JNK-deficient n...

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Bibliografiske detaljer
Main Authors: Xu, Ping, Das, Madhumita, Reilly, Judith, Davis, Roger J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042155/
https://ncbi.nlm.nih.gov/pubmed/21325132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1984311
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