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Role of JNK in a Trp53-Dependent Mouse Model of Breast Cancer

The cJun NH(2)-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BALB/c mice. We detected no defects in mammary glan...

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Bibliografische gegevens
Hoofdauteurs: Cellurale, Cristina, Weston, Claire R., Reilly, Judith, Garlick, David S., Jerry, D. Joseph, Sluss, Hayla K., Davis, Roger J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930003/
https://ncbi.nlm.nih.gov/pubmed/20814571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012469
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