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Role of JNK in a Trp53-Dependent Mouse Model of Breast Cancer
The cJun NH(2)-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BALB/c mice. We detected no defects in mammary glan...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930003/ https://ncbi.nlm.nih.gov/pubmed/20814571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012469 |
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