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Induction of hepatitis by JNK-mediated expression of TNFα
The cJun NH(2)-terminal kinase (JNK) signaling pathway has been implicated in the development of tumor necrosis factor (TNF) -dependent hepatitis. Indeed, JNK may play a critical role in hepatocytes during TNF-stimulated cell death in vivo. To test this hypothesis, we examined the phenotype of mice...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794880/ https://ncbi.nlm.nih.gov/pubmed/19167327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.017 |
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