Suppression of Ras-stimulated transformation by the JNK signal transduction pathway

The c-Jun NH(2)-terminal kinase (JNK) phosphorylates and activates members of the activator protein-1 (AP-1) group of transcription factors and is implicated in oncogenic transformation. To examine the role of JNK, we investigated the effect of JNK deficiency on Ras-stimulated transformation. We dem...

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Bibliographic Details
Main Authors: Kennedy, Norman J., Sluss, Hayla K., Jones, Stephen N., Bar-Sagi, Dafna, Flavell, Richard A., Davis, Roger J.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC196007/
https://ncbi.nlm.nih.gov/pubmed/12629045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1062903
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