Detection of changes in pairwise interactions during allosteric transitions: Coupling between local and global conformational changes in GroEL

A protein engineering approach for detecting and measuring local conformational changes that accompany allosteric transitions in proteins is described. Using this approach, we can identify interactions that are made or broken during allosteric transitions. The method is applied to probe for changes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aharoni, Amir, Horovitz, Amnon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19979/
https://ncbi.nlm.nih.gov/pubmed/9050841
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