ADD66, a Gene Involved in the Endoplasmic Reticulum-associated Degradation of α-1-Antitrypsin-Z in Yeast, Facilitates Proteasome Activity and Assembly

Antitrypsin deficiency is a primary cause of juvenile liver disease, and it arises from expression of the “Z” variant of the α-1 protease inhibitor (A1Pi). Whereas A1Pi is secreted from the liver, A1PiZ is retrotranslocated from the endoplasmic reticulum (ER) and degraded by the proteasome, an event...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Scott, Craig M., Kruse, Kristina B., Schmidt, Béla Z., Perlmutter, David H., McCracken, Ardythe A., Brodsky, Jeffrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995736/
https://ncbi.nlm.nih.gov/pubmed/17634286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0034
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky