Hsp70 Molecular Chaperone Facilitates Endoplasmic Reticulum-associated Protein Degradation of Cystic Fibrosis Transmembrane Conductance Regulator in Yeast

Membrane and secretory proteins fold in the endoplasmic reticulum (ER), and misfolded proteins may be retained and targeted for ER-associated protein degradation (ERAD). To elucidate the mechanism by which an integral membrane protein in the ER is degraded, we studied the fate of the cystic fibrosis...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Zhang, Yimao, Nijbroek, Gaby, Sullivan, Mara L., McCracken, Ardythe A., Watkins, Simon C., Michaelis, Susan, Brodsky, Jeffrey L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1303
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