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Hsp90 <i>pan</i> and Isoform-Selective Inhibitors as Sensitizers for Cancer Immunotherapy

The 90 kDa heat shock proteins (Hsp90) are molecular chaperones that regulate the stability and maturation of numerous client proteins implicated in the regulation of cancer hallmarks. Despite the potential of <i>pan</i>-Hsp90 inhibitors as anticancer therapeutics, their clinical development has bee...

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Principais autores: Shiying Jia, Neeraj Maurya, Brian S. J. Blagg, Xin Lu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-07-01
Series:Pharmaceuticals
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Acceso en liña:https://www.mdpi.com/1424-8247/18/7/1025
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