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Hsp70 Molecular Chaperone Facilitates Endoplasmic Reticulum-associated Protein Degradation of Cystic Fibrosis Transmembrane Conductance Regulator in Yeast

Membrane and secretory proteins fold in the endoplasmic reticulum (ER), and misfolded proteins may be retained and targeted for ER-associated protein degradation (ERAD). To elucidate the mechanism by which an integral membrane protein in the ER is degraded, we studied the fate of the cystic fibrosis...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhang, Yimao, Nijbroek, Gaby, Sullivan, Mara L., McCracken, Ardythe A., Watkins, Simon C., Michaelis, Susan, Brodsky, Jeffrey L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Cell Biology 2001
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC34585/
https://ncbi.nlm.nih.gov/pubmed/11359923
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