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Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response

The serine proteinase inhibitor α-1 antitrypsin (AAT) is produced principally by the liver at the rate of 2 g/d. It is secreted into the circulation and provides an antiprotease protective screen throughout the body but most importantly in the lung, where it can neutralise the activity of the serine...

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Detalles Bibliográficos
Main Authors: Greene, Catherine M, McElvaney, Noel G
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091154/
https://ncbi.nlm.nih.gov/pubmed/21577302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4292/wjgpt.v1.i5.94
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