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Selenoprotein S/SEPS1 Modifies Endoplasmic Reticulum Stress in Z Variant α(1)-Antitrypsin Deficiency
Z α(1)-antitrypsin (ZAAT) deficiency is a disease associated with emphysematous lung disease and also with liver disease. The liver disease of AAT deficiency is associated with endoplasmic reticulum (ER) stress. SEPS1 is a selenoprotein that, through a chaperone activity, decreases ER stress. To det...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719325/ https://ncbi.nlm.nih.gov/pubmed/19398551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006288 |
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