Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington’s disease

A yeast artificial chromosome (YAC) mouse model of Huntington’s disease (YAC128) develops motor abnormalities, age-dependent striatal atrophy and neuronal loss. Alteration of neurotransmitter receptors, particularly glutamate and dopamine receptors, is a pathological hallmark of Huntington’s disease...

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Hlavní autoři: Benn, Caroline L., Slow, Elizabeth J., Farrell, Laurie A., Graham, Rona, Deng, Yu, Hayden, Michael R., Cha, Jang-Ho J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995552/
https://ncbi.nlm.nih.gov/pubmed/17544587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.03.010
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