Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide expansion in the HD gene, resulting in an extended polyglutamine tract in the protein huntingtin. HD is traditionally viewed as a movement disorder, but cognitive and neuropsychiatric symptom...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: de Paula Nascimento-Castro, Cristine, Wink, Ana Claudia, da Fônseca, Victor Silva, Bianco, Claudia Daniele, Winkelmann-Duarte, Elisa C., Farina, Marcelo, Rodrigues, Ana Lúcia S., Gil-Mohapel, Joana, de Bem, Andreza Fabro, Brocardo, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112232/
https://ncbi.nlm.nih.gov/pubmed/30186318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4056383
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