Analysis of the Inhibition of Mammalian Carboxylesterases by Novel Fluorobenzoins and Fluorobenzils

We have synthesized and assessed the ability of symmetrical fluorobenzoins and fluorobenzils to inhibit mammalian carboxylesterases (CE). The majority of the latter were excellent inhibitors of CEs however unexpectedly, the fluorobenzoins were very good enzyme inhibitors. Positive correlations were...

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Bibliographic Details
Main Authors:	Hicks, Latorya D., Hyatt, Janice L, Moak, Teri, Edwards, Carol C., Tsurkan, Lyudmila, Wierdl, Monika, Ferreira, Antonio, Wadkins, Randy M., Potter, Philip M.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1995442/ https://ncbi.nlm.nih.gov/pubmed/17399985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.03.012
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Analysis of the Inhibition of Mammalian Carboxylesterases by Novel Fluorobenzoins and Fluorobenzils

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