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The nature of telomere fusion and a definition of the critical telomere length in human cells
The loss of telomere function can result in telomeric fusion events that lead to the types of genomic rearrangements, such as nonreciprocal translocations, that typify early-stage carcinogenesis. By using single-molecule approaches to characterize fusion events, we provide a functional definition of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1993879/ https://ncbi.nlm.nih.gov/pubmed/17908935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.439107 |
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