The nature of telomere fusion and a definition of the critical telomere length in human cells

The loss of telomere function can result in telomeric fusion events that lead to the types of genomic rearrangements, such as nonreciprocal translocations, that typify early-stage carcinogenesis. By using single-molecule approaches to characterize fusion events, we provide a functional definition of...

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Autors principals: Capper, Rebecca, Britt-Compton, Bethan, Tankimanova, Maira, Rowson, Jan, Letsolo, Boitelo, Man, Stephen, Haughton, Michele, Baird, Duncan M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993879/
https://ncbi.nlm.nih.gov/pubmed/17908935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.439107
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