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Telomere Length Dynamics and the Evolution of Cancer Genome Architecture

Telomeres are progressively eroded during repeated rounds of cell division due to the end replication problem but also undergo additional more substantial stochastic shortening events. In most cases, shortened telomeres induce a cell-cycle arrest or trigger apoptosis, although for those cells that b...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Cleal, Kez, Norris, Kevin, Baird, Duncan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855704/
https://ncbi.nlm.nih.gov/pubmed/29415479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020482
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