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Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain

Intracerebral administration of the excitotoxin ibotenate to newborn mice induces white-matter lesions, mimicking brain lesions that occur in human preterm infants. Nociceptin (NC), also called orphanin FQ, is the endogenous ligand of the opioid receptor-like 1 (ORL1) receptor and does not bind clas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Laudenbach, Vincent, Calo, Girolamo, Guerrini, Remo, Lamboley, Géraldine, Benoist, Jean-François, Evrard, Philippe, Gressens, Pierre
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC199242/
https://ncbi.nlm.nih.gov/pubmed/11181645
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