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Initial TCR-transgenic precursor frequency dictates critical aspects of the CD8 T cell response to infection
Adoptive transfer experiments with relatively large input numbers (~10(6)) of TCR-transgenic T-cells are widely used to model endogenous T-cell responses to infection or immunization. Here, we show that input numbers of naïve TCR-tg T cells sufficient to squelch the endogenous response to the same e...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1989155/ https://ncbi.nlm.nih.gov/pubmed/17555991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.04.013 |
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