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Constitutive activation of Wnt signaling favors generation of memory CD8 T cells

TCF-1 and LEF-1, the effector transcription factors of the canonical Wnt pathway, are known to be critical for normal thymocyte development. However, it is largely unknown if it has a role in regulating mature T cell activation and T cell-mediated immune responses. Here we demonstrate that like IL-7...

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Hlavní autoři: Zhao, Dong-Mei, Yu, Shuyang, Zhou, Xinyuan, Haring, Jodie S., Held, Werner, Badovinac, Vladimir P., Harty, John T., Xue, Hai-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809813/
https://ncbi.nlm.nih.gov/pubmed/20026746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901199
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