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Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1

T cell factor 1 (TCF-1) is a transcription factor known to act downstream of the canonical Wnt pathway and is essential for normal T cell development. However, its physiological roles in mature CD8(+) T cell responses are unknown. Here we showed that TCF-1 deficiency limited proliferation of CD8(+)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhou, Xinyuan, Yu, Shuyang, Zhao, Dong-Mei, Harty, John T., Badovinac, Vladimir P., Xue, Hai-Hui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928475/
https://ncbi.nlm.nih.gov/pubmed/20727791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.08.002
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