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Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1
T cell factor 1 (TCF-1) is a transcription factor known to act downstream of the canonical Wnt pathway and is essential for normal T cell development. However, its physiological roles in mature CD8(+) T cell responses are unknown. Here we showed that TCF-1 deficiency limited proliferation of CD8(+)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928475/ https://ncbi.nlm.nih.gov/pubmed/20727791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.08.002 |
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