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Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation
Repetitive antigen-stimulation by prime-boost vaccination or pathogen re-encounter increases memory CD8(+) T cell numbers, however the impact on memory CD8(+) T cell differentiation is unknown. Here we showed that repetitive antigen-stimulations induced accumulation of memory CD8(+) T cells with uni...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912220/ https://ncbi.nlm.nih.gov/pubmed/20619696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.014 |
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