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Generation of memory precursors and functional memory CD8(+) T cells depends on TCF-1 and LEF-1
TCF-1 and LEF-1 transcription factors have redundant roles in promoting thymocyte maturation. TCF-1 has been recently shown to critically regulate memory CD8(+) T cell differentiation and persistence. The complete spectrum of regulatory roles for TCF-1 and LEF-1 in CD8(+) T cell responses are yet un...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437003/ https://ncbi.nlm.nih.gov/pubmed/22875805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201150 |
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