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Generation of memory precursors and functional memory CD8(+) T cells depends on TCF-1 and LEF-1

TCF-1 and LEF-1 transcription factors have redundant roles in promoting thymocyte maturation. TCF-1 has been recently shown to critically regulate memory CD8(+) T cell differentiation and persistence. The complete spectrum of regulatory roles for TCF-1 and LEF-1 in CD8(+) T cell responses are yet un...

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Bibliografiske detaljer
Main Authors: Zhou, Xinyuan, Xue, Hai-Hui
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437003/
https://ncbi.nlm.nih.gov/pubmed/22875805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201150
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