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Constitutive activation of Wnt signaling favors generation of memory CD8 T cells
TCF-1 and LEF-1, the effector transcription factors of the canonical Wnt pathway, are known to be critical for normal thymocyte development. However, it is largely unknown if it has a role in regulating mature T cell activation and T cell-mediated immune responses. Here we demonstrate that like IL-7...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809813/ https://ncbi.nlm.nih.gov/pubmed/20026746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901199 |
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