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FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein

The BRCA1 associated C-terminal helicase (BACH1, designated FANCJ) is implicated in the chromosomal instability genetic disorder Fanconi anemia (FA) and hereditary breast cancer. A critical role of FANCJ helicase may be to restart replication as a component of downstream events that occur during the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gupta, Rigu, Sharma, Sudha, Sommers, Joshua A., Kenny, Mark K., Cantor, Sharon B., Brosh, Robert M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988918/
https://ncbi.nlm.nih.gov/pubmed/17596542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-057273
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