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Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand

The BRCA1 associated C-terminal helicase (BACH1) associated with breast cancer has been implicated in double strand break (DSB) repair. More recently, BACH1 (FANCJ) has been genetically linked to the chromosomal instability disorder Fanconi Anemia (FA). Understanding the roles of BACH1 in cellular D...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gupta, Rigu, Sharma, Sudha, Doherty, Kevin M., Sommers, Joshua A., Cantor, Sharon B., Brosh, Robert M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751539/
https://ncbi.nlm.nih.gov/pubmed/17145708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl964
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