FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response

BRCA1 promotes DNA repair through interactions with multiple proteins, including CtIP and FANCJ (also known as BRIP1/BACH1). While CtIP facilitates DNA end resection when de-acetylated, the function of FANCJ in repair processing is less well defined. Here, we report that FANCJ is also acetylated. Pr...

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Autori principali: Xie, Jenny, Peng, Min, Guillemette, Shawna, Quan, Steven, Maniatis, Stephanie, Wu, Yuliang, Venkatesh, Aditya, Shaffer, Scott A., Brosh, Robert M., Cantor, Sharon B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390368/
https://ncbi.nlm.nih.gov/pubmed/22792074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002786
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